Gamete Intrafallopian Transfer (GIFT) is a fertility treatment that involves collecting eggs and sperm from a couple and then placing them directly into the fallopian tubes, allowing fertilization to occur naturally. This procedure was first introduced in the 1980s and was considered an alternative to in vitro fertilization (IVF). However, GIFT has its own set of risks and complications that couples should be aware of before undergoing the procedure.
One of the main risks of GIFT is the possibility of multiple pregnancies. Since multiple eggs are placed into the fallopian tubes, there is a higher chance of more than one egg being fertilized and resulting in a multiple pregnancy. This can increase the risk of complications such as premature delivery, low birth weight, and the need for a cesarean section. It is important for couples to discuss the potential risks of multiple pregnancies with their doctor before deciding to undergo GIFT.
Another potential risk of GIFT is ovarian hyperstimulation syndrome (OHSS). This is a condition in which the ovaries become enlarged and produce too many eggs in response to fertility medications. OHSS can cause symptoms such as bloating, abdominal pain, and difficulty breathing. In severe cases, it can lead to hospitalization and even life-threatening complications. While OHSS is rare with GIFT, couples should be aware of the signs and symptoms and seek medical attention if they experience them.
In addition, there is a risk of infection with GIFT, as with any medical procedure. The eggs and sperm are collected from the couple’s bodies and then placed into the fallopian tubes, which can introduce bacteria and other microorganisms. This can lead to pelvic inflammatory disease (PID) or other infections in the reproductive organs. To reduce the risk of infection, it is important to follow your doctor’s instructions for caring for the incision site and to report any signs of infection, such as fever or increased pain, immediately.

The Risks and Complications of Gamete Intrafallopian Transfer
One of the major complications of GIFT is the failure of fertilization or implantation. While GIFT is designed to facilitate fertilization in a natural environment, there is still a chance that the eggs and sperm will not meet or that the fertilized egg will not implant in the uterus. This can be emotionally and financially taxing for couples who have invested time and money into the procedure. It is important for couples to understand that GIFT, like any fertility treatment, is not a guarantee of success.
Another potential complication of GIFT is ectopic pregnancy, where the fertilized egg implants outside of the uterus, usually in the fallopian tubes. This can be life-threatening if not diagnosed and treated early. Ectopic pregnancies are more common with GIFT than with other fertility treatments, as the eggs are placed directly into the fallopian tubes where they can become stuck. It is important for couples to be aware of the signs and symptoms of ectopic pregnancy, such as abdominal pain and vaginal bleeding, and to seek medical attention immediately if they experience them.
Lastly, there is a risk of emotional and psychological complications with GIFT. Fertility treatments can be emotionally taxing for couples, and the anticipation and disappointment of failed fertilization or implantation can take a toll on their mental health. It is important for couples to have a strong support system and to seek counseling if needed during this process.
In summary, while GIFT may seem like a less invasive and more natural option for fertility treatment, it still carries its own set of risks and complications. Multiple pregnancies, OHSS, infection, fertilization or implantation failure, ectopic pregnancy, and emotional and psychological complications are all potential risks that couples should be aware of before undergoing GIFT. It is important for individuals to discuss these risks with their doctor and carefully weigh the pros and cons before deciding on this procedure.